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The etiology and pathogenesis of reticulohistiocytosis are not completely known. The possibility of a viral or bacterial infection is assumed (in the anamnesis of children, infections are often noted - tonsillitis, otitis media, sepsis, etc.). The steadily progressive course of the disease may indicate the neoplastic nature of the process. A. M. Abezgauz believed that the genetic mutation factor is of great importance in the pathogenesis of the disease. Symptoms of reticulohistiocytosis. The disease usually begins in infancy, sometimes even in the neonatal period, with a sudden rise in temperature to 40 �� C. Then the temperature curve acquires a hectic character, but sometimes it can be subfebrile. On the scalp, in the area of �6�7�6�7the shoulder blades, abdomen and chest, a lot of hemorrhagic scaly lichenoid papules and petechial elements appear.